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After a while, the brain adjusts to the excess dopamine, which decreases the higher that the person feels in comparison to the higher they felt when first taking the drug?�an outcome often called tolerance. They could acquire far more on the drug, making an attempt to attain exactly the same dopamine high.

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Cigarette smoking or injecting drugs can improve the opportunity for addiction. Using drugs viewed as less addicting ??so-known as "gentle drugs" ??can start out you on a pathway of drug use and addiction.